Open science achieves its full potential when data, instruments, and publications are linked within a transparent and interoperable ecosystem. This Open Access Week 2025 session—hosted by Dr. Shuhan He and Amy Avakian MD of ConductScience.org—examines how reproducibility and data integration can be engineered into the research lifecycle itself.
The discussion will explore practical and technical approaches for building sustainable open-infrastructure frameworks, including:
- Embedding structured, machine-readable metadata and UMLS-linked identifiers within publications to support semantic search and re-use
- Incorporating persistent hardware identifiers (HIDs) for traceable instrument provenance and calibration data
- Applying the S-Index, a novel data metric, to quantify the impact of data-sharing and reproducibility
- Ensuring that outputs from behavioral and neurotechnological experiments are FAIR-compliant (Findable, Accessible, Interoperable, Reusable) by design
- Linking experimental data, metadata schemas, and open-access publications through automated integration pipelines.

Drawing on ongoing work within the ConductScience.org open-publishing ecosystem and its collaborations across academic partners, the event presents a conceptual and technical blueprint for data-integrated open science. Participants will gain insight into how standardization and open design can advance reproducibility, equity, and measurable scientific impact.